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RESOLVE examples

Removal of model bias with prime-and-switch phasing
 IF5A molecular replacement phasing
 Dehalogenase molecular replacement phasing
Improvement of experimentally- phased maps
 IF5A MAD map


Removal of model bias with prime-and-switch phasing

IF5A molecular replacement phasing




Removal of model bias with prime-and-switch phasing

Dehalogenase molecular replacement phasing



Improvement of experimentally-phased maps
IF5A MAD map

(See: Peat, T. S., Newman, J., Waldo, G. S., Berendzen, J. & Terwilliger, T. C. (1998) "Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 A resolution" Structure 15, 1207-1214.

Initial MAD map (CC=0.37)
 
 

RESOLVE map (CC=0.79)
 
 

Conventional solvent flattening & histogram matching (CC=0.65)